In a world both more connected and more ecologically compromised, health risks will continue to be a challenge. The COVID-19 pandemic threw into sharp relief our individual and collective vulnerability, as well as the deep inequalities in care and access that pervade our societies—lessons that were present in former pandemics and epidemics, from HIV/AIDS to Ebola. But the risks are not only viral: pollution and environmental degradation continue to harm communities. Sexual and reproductive rights are increasingly understood as a fundamental part of health. Societal responses to drug addiction and even violence are being informed more and more by medical and health research. How can the human rights movements help center the health and well-being of all as an organizing priority for our societies?